The aim of this course is to present a cutting edge update on imaging and therapeutic hot-topics in the retina space, as well as the application of AI and robotics in clinical practice. Different retinal diseases will be addressed, including the ROP.

The topic is retinal detachment with proliferative vitreoretinopathy. In this course we will describe the main risk factors, the genetic predisposition and the vitreoretinal surgery of PVR, with the need or not of scleral buckling, lensectomy associated to vitrectomy in PVR, the surgical steps, the dissection of the proliferative tissue using PFCL and different stainings to improve the identification and dissection of the membranes, the importance of ILM dissection to prevent macular PVR, how to manage pediatric PVR, how to dissect the posterior hyaloid in these patients. We will also discuss the indications and technique of relaxing retinotomy, the best endotamponade agents. Traumatic PVR will be extensively explained, and the use of a combined technique of viscodissection and PFCL to open closed funnels. We will also discuss the different methods to prevent recurrent PVR, including Metotrexate. Some clinical cases will be presented and the audience will know the opinion of all the instructors, which will explain how to manage them, which surgery to employ. We will present didactic talks with scheduled questions and answers managed by the course director, discussion among panelists and with the audience, clinical cases of proliferative vitreoretinopathy with panel discussion, and a final summary with the take home messages of each presentation. The main objective of this course is that in conclusion of the talks of the proposed instructors and the discussion that attendee will be able to understand the process of PVR, the new surgical techniques employed and the prognostic factors of success. We want an interactive course with participation of the audience.

Diabetic macular edema (DME) remains a leading cause of vision loss among working-age adults, yet its management continues to evolve rapidly with advances in imaging, pharmacotherapy, and personalized care. This instructional course provides a comprehensive, evidence-based overview of contemporary DME management in 2026, integrating pathophysiology with practical treatment strategies. Participants will review the role of vascular endothelial growth factor (VEGF), inflammation, and systemic factors in DME development, alongside the latest diagnostic approaches including OCT biomarkers and multimodal imaging. The course will emphasize individualized treatment paradigms, highlighting first-line anti-VEGF therapies, emerging longer-acting agents, and the expanding role of corticosteroid implants in selected patients. Through case-based discussions and practical algorithms, attendees will gain actionable insights into tailoring therapy, improving visual outcomes, and minimizing complications. By the end of the course, participants will be equipped with up-to-date knowledge and clinical tools to deliver personalized, efficient, and durable care for patients with DME in modern practice.

The choroid is a central anatomical structure, particularly important for the nourishment and metabolic support of the outer retina, including the photoreceptors and retinal pigment epithelium. Therefore, it is likely to play a significant role in the pathogenesis and progression of age-related macular degeneration (AMD). In recent years, advances in imaging technologies—especially enhanced depth imaging optical coherence tomography (EDI-OCT) and swept-source OCT—combined with artificial intelligence (AI)-based analysis have substantially improved our understanding of the choroid and its complex involvement in AMD. These developments allow for a more precise visualization and quantification of choroidal thickness, vascular structure, and biomarkers such as pachyvessels or choriocapillaris alterations. As a result, distinct choroidal patterns can now be associated with different AMD phenotypes, including Geographic Atrophy, pachychoroid spectrum diseases, and neovascular AMD. This course will focus on the interpretation of choroidal OCT findings and their relevance across various AMD subtypes. Particular emphasis will be placed on how these insights may refine our understanding of disease mechanisms and support more individualized treatment strategies, including anti-VEGF therapy and emerging therapeutic approaches.

The prevalence of myopia is rapidly growing and is an epidemic in many parts of the globe. Due to advances in imaging, there have been a number of novel insights in recent years regarding the pathophysiology and progression of this disorder. These insights provide avenues towards novel therapeutics which may improve the outlook and prognosis for patients with this disease. This course brings together a number of global experts on this topic to prevent the latest advances in our understanding of pathophysiology that have been informed my multimodal imaging.